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  • 31 Mar 2021 1:14 PM | ISDE Office (Administrator)

    Comparison of Esophagectomy outcomes between a National Center, a National Audit Collaborative, and an International database using the Esophageal Complications Consensus Group (ECCG) standardized definitions
    DOTE Featured Article
    Members Only Access

    The ECCG developed a standardized platform for reporting operative complications, with consensus definitions. The Dutch Upper Gastrointestinal Cancer Audit (DUCA) published a national comparison against these benchmarks. This study compares ECCG data from the Irish National Center (INC) with both published benchmark studies. All patients undergoing multimodal therapy or surgery with curative intent from 2014 to 2018 inclusive were studied, with data recorded prospectively and entered onto a secure online database (Esodata.org). Read the full Comparison of Esophagectomy outcomes between a National Center article.

  • 31 Mar 2021 1:11 PM | ISDE Office (Administrator)

    Effect of anastomotic leaks on long-term survival after oesophagectomy for oesophageal cancer: systematic review and meta-analysis
    DOTE Volume 34, Issue 3 | Editor's Choice
    Free Article

    Long-term survival after curative surgery for oesophageal cancer surgery remains poor, and the prognostic impact of anastomotic leak (AL) remains unknown. A meta-analysis was conducted to investigate the impact of AL on long-term survival. Read the full Effect of anastomotic leaks on long-term survival article for free.

    Abandoning resectional intent in patients initially deemed suitable for esophagectomy: a nationwide study of risk factors and outcomes
    DOTE Volume 34, Issue 3 | Editor's Choice
    Free Article

    The main curative treatment modality for esophageal cancer is resection. Patients initially deemed suitable for resection may become unsuitable, most commonly due to signs of generalized disease or having become unfit for surgery. The aim was to assess risk factors for abandoning esophagectomy and its impact on survival. All patients diagnosed with an esophageal or gastroesophageal junction cancer in the Swedish National Register for Esophageal and Gastric Cancer from 2006–2016 were included and risk factors associated with becoming ineligible for resection were analyzed in multivariable logistic regression analysis. Read the full Abandoning resectional intent in patients article for free.

  • 31 Mar 2021 1:11 PM | ISDE Office (Administrator)

    Review a collection of the top ten articles from recent years and stay up-to-date on research that’s making the largest impact in the field, including the following:

    • Comparison of short-term outcomes between robot-assisted minimally invasive esophagectomy and video-assisted minimally invasive esphagectomy in treating middle thoracic esophageal cancer
    • Nutritional optimization during neoadjuvant therapy prior to surgical resection of esophageal cancer – a narrative review
    • Neoadjuvant chemotherapy versus neoadjuvant chemoradiotherapy for cancer of the esphagus or gastroesophageal junction: long-term results of a randomized clinical trial
    • Economic and survival burden of dysphagia among inpatients in the United States
    • The 2018 ISDE achalasia guidelines

    Checkout the reading list online for the complete list.

  • 31 Mar 2021 1:10 PM | ISDE Office (Administrator)

    Checkout the latest DOTE issue for articles on Benign Esophageal and Malignant Esophageal Diseases; See the full table of contents.

  • 31 Mar 2021 1:09 PM | ISDE Office (Administrator)

    We are pleased to announce that we received close to 600 abstract submissions for the ISDE 2021 Virtual Congress! The program committee is looking forward to reviewing all proposals and we will send out result notifications in May.

    Watch this space for the preliminary scientific program – it will be announced on the congress website very soon.

    Next month will also see the opening of the congress registrations.

  • 29 Mar 2021 7:30 PM | ISDE Office (Administrator)

    Among the most exotic locations for an ISDE World Congress was Kyoto, the site of the 5th World Congress (Figure 1). This meeting was hosted by Congress President Prof. Kin-ichi Nabeya (Figure 2), and the ISDE President was Prof. David Skinner in August 1992. Attendance was 650 strong, representing 45 countries. Submitting abstracts numbered over 500, representing 32 countries. The attendees and accompanying persons enjoyed the beauty and culture of Kyoto immensely (Figure 3). Side trips included a visit to an old capitol of Japan, Nara, and many attendees tried out a traditional ryokan (bed and breakfast) to experience what life was like a century or more before. ISDE milestones marked during this Congress included incorporation of the journal Gullet, edited by Prof. Glyn Jamieson, into Diseases of the Esophagus, and Prof J. Rudiger Siewert succeeded Prof Sergio Stipa as journal editor. The Congress proceedings were published by Springer as Recent Advances in Diseases of the Esophagus, edited by Profs. Nabeya and Hanaoka and Dr. Nogami (Figure 4), which included over 1,000 chapters covering all aspects of esophageal disease.

    The 6th ISDE was held in the international design capital of Milan, Italy, in August 1995. The ISDE President was Prof. Skinner, and the hosts were Congress President Prof. Alberto Peracchia (Figure 5) and his colleague, Prof. Ermanno Ancona. The program was outstanding, including 51 invited lectures, 365 oral abstracts, 108 posters, 68 videos, and a memorable lecture by Mr. Ronald Belsey on the history of clinical esophagology. Over 750 attendees represented nearly 40 different countries. Interest was expressed in encouraging broader membership outside of surgery, and appropriate changes were made to the constitution and bylaws to permit this. The social program was highlighted by regional dress (Figure 6) and, of course, by operatic music (Figure 7). The proceedings were published as Recent Advances in Diseases of the Esophagus, containing more than 1,100 pages divided into 20 sections and including more than 700 authors. It was edited by Peracchia, Rosati, Bonavina, Fumagalli, Bona, and Chella.

    Figure 1. The announcement for the 5th ISDE World Congress.

    Figure 2. Prof. Nabeya, his wife, and Prof. Toni Lerut at the 5th ISDE World Congress.

    Figure 3. Social events included learning traditional flower arranging.

    Figure 4. Recent Advances in Diseases of the Esophagus was published based on proceedings of the 5th ISDE Congress.

    Figure 5. Prof. Peracchia, President of the 6th ISDE World Congress.


    Figure 6. Prof. Peracchia greeting by city officials during the opening ceremonies.

    Figure 7. An enthusiastic rendering of a favorite Italian operatic piece.


  • 26 Mar 2021 7:39 PM | Anonymous


    Esophageal cancer is among the 6th to 8th cause of cancer mortality according to the Global Cancer Observatory. The esophagus is a muscular tube that connects the throat to the stomach. Its symptoms cause a significant impact on patients lives and are often: swallow disorder (dysphagia), unintentional weight loss, heartburn and chest pain. The early treatment for esophageal cancer is imperative for a better prognosis and enhances the chance of the patient survivor. Esophagectomy has an important role in the cancer treatment and minimally invasive approach has been achieving an increasingly solid result in recent years.

    The ISDE hosted a virtual tumour board on the multidisciplinary management of esophageal neoplasm that touched on cancer surgery, oncological treatment, management of surgery complications and endoscopic treatment. This live event was held on March 23, 2021 and moderated by Simon Law, University of Hong Kong (Hong Kong) and Richard van Hillegersberg, University Medical Center Utrecht (The Netherlands).


    Case 1 | Post chemoradiation esophageal stenosis


    Case 2 | Shifting boundaries in T1b esophageal cancer


    Case 3 | Oligometastatic disease

    Case 3 recording can only be viewed on Youtube. Click the image to view.



    Case 4 | Unresectable Case

    ISDE wishes to recognize and thank the following individuals for their contributions to this virtual tumour board:

    • Trevor Leong, Radiation Oncologist, Peter MacCallum Cancer Centre (Australia)
    • Daniela Molena, Surgeon, Memorial Sloan Kettering Cancer Center (USA)
    • Ken Kato, Medical Oncologist, National Cancer Center Hospital (Japan)
    • Christiane Bruns, Surgeon, University Hospital Cologne (Germany)
    • Jacques Bergman, Gastroenterologist (The Netherlands)

    If you are interested in this you may also be interested in the Esophageal Cancer Playlist too.

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  • 26 Feb 2021 4:21 PM | ISDE Office (Administrator)

    The ISDE is happy to endorse programs of sufficient relevance and quality developed by other societies or organizations that align with its mission. Endorsed meetings will appear on the Industry Events section of the ISDE website, in the newsletter and on social media. For more information and to receive a copy of the ISDE Policy on Meeting Endorsement please contact info@isde.net.


  • 26 Feb 2021 4:19 PM | ISDE Office (Administrator)

    DOTE Volume 34, Issue 2 | Editor's Choice
    Free Article

    Achalasia Quality of Life (ASQ) and Eckardt scores are two patient-reported instruments widely used to assess symptom severity in achalasia patients. ASQ is validated and reliable. Although Eckardt is commonly used, it has not been rigorously assessed for validity or reliability. This study aims to evaluate (i) the accuracy of Eckardt and ASQ for assessing improvement post-treatment (predictive validity), (ii) accuracy of Eckardt and ASQ for assessing improvement post-treatment with pneumatic dilatation (PD) versus surgical myotomy (predictive validity), and (iii) convergent validity of Eckardt and ASQ tools. Read the full accuracy of achalasia quality of life article for free.

  • 26 Feb 2021 4:17 PM | ISDE Office (Administrator)

    DOTE Volume 34, Issue 2 | Editor's Choice
    Free Article

    Esophagectomy is the gold-standard treatment for esophageal cancer; however, postoperative anastomotic leakage remains the primary concern for surgeons. No consensus exists on the optimal investigations to predict an anastomotic leak. This systematic review aims to identify a single test or combination of tests with acceptable sensitivity and specificity to identify anastomotic leak after esophagectomy and to formulate a diagnostic algorithm to facilitate surgical decision-making. Read the full diagnosing anastomotic article for free.

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